Publications by authors named "J C Naudin"

Background: Most children admitted to a paediatric intensive care unit (PICU) now survive because of improvements in care. Many studies have identified the psychological, functional, cognitive and social impact of PICU admission on a child and their family. However, expert recommendations on follow-up are lacking.

View Article and Find Full Text PDF

Introduction: In children, respiratory distress due to upper airway obstruction (UAO) is a common complication of extubation. The quantitative cuff-leak test (qtCLT) is a simple, rapid and non-invasive test that has not been extensively studied in children. The objective of the ongoing study whose protocol is reported here is to investigate how well the qtCLT predicts UAO-related postextubation respiratory distress in paediatric intensive care unit (PICU) patients.

View Article and Find Full Text PDF
Article Synopsis
  • A study evaluated the effectiveness of the BioFire Pneumonia plus Panel, a rapid-multiplex PCR assay, in diagnosing lower-respiratory-tract infections in critically ill pediatric patients compared to traditional culturing methods.
  • It included 36 patients with varying types of pneumonia and found that the PCR assay had high sensitivity (92%) and specificity (95%), with a notable agreement between the two methods (κ = 0.74).
  • The PCR assay also provided faster results (about 3.9 hours) than the reference method (about 60.5 hours), potentially leading to better-targeted antibiotic treatments and reduced unnecessary antibiotic use.
View Article and Find Full Text PDF

Background: Sickle cell disease (SCD) is one of the most frequent inherited diseases in the world. Over the last decades, in high-income countries, an important decrease in mortality have been observed due to the improvement of care. However, children with SCD can become critically ill and require admission in Pediatric Intensive Care Units (PICU).

View Article and Find Full Text PDF