Publications by authors named "J C Marcos"
Article Synopsis
- Antifungal proteins (AFPs), particularly PeAfpA from Penicillium expansum, exhibit strong antifungal activity, though their mechanisms remain unclear.
- PeAfpA influences the morphology and growth of P. digitatum without causing a spike in reactive oxygen species like the less effective PdAfpB.
- Live-cell imaging showed PeAfpA's dynamic interaction with various P. digitatum states, leading to its eventual internalization in hyphae and triggering cell death, providing insights for future biofungicide development.
Article Synopsis
- This study investigates the prevalence of axial spondylarthritis (axSpA) in young people with chronic low back pain (LBP) using the ASAS 2009 criteria, focusing on data from a university hospital in Buenos Aires, Argentina.
- Among 795 patients reviewed, the estimated prevalence of axSpA was about 5.78%, with a notable proportion (21.74%) of cases being undiagnosed.
- The findings suggest that the high rate of undiagnosed axSpA could contribute to the lower prevalence rates previously reported in Latin America.
The control of heat-resistant fungi (HRFs), which cause spoilage of heat-treated fruit products, is considered a challenge for the fruit juice and beverage industry and requires new strategies for the development of antifungal compounds. In this study, four antifungal proteins (AFPs) from Penicillium digitatum (PdAfpB) and Penicillium expansum (PeAfpA, PeAfpB and PeAfpC), were evaluated against conidia from a representative collection of HRFs. A total of 19 strains from 16 different species belonging to the genera Aspergillus, Hamigera, Paecilomyces, Rasamsonia, Sarocladium, Talaromyces and Thermoascus were included in the study.
View Article and Find Full Text PDFThe training of hospital pharmacists in the coming years must adapt and respond to constant current and future social and technological challenges, without neglecting the basic areas of the profession. It is necessary to acquire knowledge in what is known as digital comprehensive health: artificial intelligence, technology and automation, digital skills, and new forms of communication with patients, such as telemedicine and telepharmacy that are already a reality in many hospitals. We must provide knowledge in automated systems for the distribution and dispensing of medicines, robots for preparing sterile preparations, traceability systems, the use of drones in clinical care, etc.
View Article and Find Full Text PDFThe training of hospital pharmacists in the coming years must adapt and respond to constant current and future social and technological challenges, without neglecting the basic areas of the profession. It is necessary to acquire knowledge in what is known as digital comprehensive health: Artificial intelligence, technology and automation, digital skills, and new forms of communication with patients, such as telemedicine and telepharmacy that are already a reality in many hospitals. We must provide knowledge in automated systems for the distribution and dispensing of medicines, robots for preparing sterile preparations, traceability systems, the use of drones in clinical care, etc.
View Article and Find Full Text PDF