This qualitative study was carried out with 30 high-risk pregnant women from a Brazilian referral service in women's health. The objective was to analyze the perception of participants regarding their condition, emphasizing their psychosocial needs, to deepen the understanding of subjective, relational, and sociocultural aspects associated with high-risk pregnancy. Data were collected through interviews and participant observation and then explored by thematic content analysis.
View Article and Find Full Text PDFPurpose: The cancer/testis antigen New York esophageal squamous cell carcinoma 1 (NY-ESO-1) is a promising target in myxoid/round cell liposarcoma (MRCLS).
Methods: In this pilot study, we assessed the adoptive T-cell therapy NY-ESO-1cT letetresgene autoleucel (lete-cel) in patients with human leukocyte antigen (HLA)-A*02:01-, HLA-A*02:05-, and/or HLA-A*02:06-positive advanced/metastatic NY-ESO-1-expressing MRCLS. Patients underwent a reduced-dose (cohort 1) or standard-dose (cohort 2) lymphodepletion regimen (LDR).
During a survey of the genus Trichoderma in the Brazilian ecosystem Restinga, 22 strains related to Trichoderma spirale were found on the basis of identities of tef1, the molecular marker used to discriminate species of this genus. Trichoderma spirale was described in 1991 and since then four species related to it were described and later on added to the clade Spirale. Searches for tef1 sequences assigned to T.
View Article and Find Full Text PDFNicotine is one of the most toxic substances found in cigarettes, but also found in chewing tobacco gum, patches and vaping products (electronic cigarettes). In addition to being a highly addictive chemical, it is capable of reducing fertility in men and women. In the ovaries, it can induce morphological changes and impair the formation of follicles, being a possible cause of changes in the reproductive cycle and anticipation of menopause in women whose mothers smoked during pregnancy.
View Article and Find Full Text PDFBackground: Temporomandibular disorder (TMD) involves various conditions affecting the anatomy and functional characteristics of the temporomandibular joint (TMJ). Hence, this study evaluated pain perception and morbidity after dental implant surgeries in patients with and without TMD.
Material And Methods: It is a prospective randomized clinical trial with 50 participants with and without TMD, randomly selected for rehabilitation procedures with dental implants.