Publications by authors named "J C M Hendriks"
Objective: To explore medical students' perceptions and experiences regarding the surgery clerkship and surgeons.
Design: Between November 2021 and February 2022, an anonymous prepost survey study was performed among 2 consecutive cohorts of medical students. The survey was taken 6 weeks prior to the surgery clerkship and repeated shortly after the surgery clerkship.
Background: To investigate the long-term efficacy of the paclitaxel-eluting Legflow balloon catheter in the treatment of "real-world" long and complex femoropopliteal lesions.
Methods: The REFLOW study was a prospective, multi-national, non-randomized, single arm study evaluating the long-term safety and efficacy of the Legflow paclitaxel-eluting balloon dilatation catheter in the treatment of stenotic or occlusive lesions >150 mm long in the femoropopliteal arteries of symptomatic patients (Rutherford 2-5). A total of 120 study subjects were enrolled in a period of 30 months, between October 2015 and May 2018.
Article Synopsis
- Pleural mesothelioma (PM) is a rare and aggressive cancer often diagnosed late, highlighting the need for early detection biomarkers through DNA methylation analysis.
- This study generated a large dataset comparing DNA methylation patterns between healthy pleura and PM, identifying over 81,000 differentially methylated sites, including five key sites linked to specific genes.
- The findings indicate that PM has unique methylation profiles that distinguish it from other lung diseases and may aid in understanding the disease’s progression and offer potential for biomarker development.
Article Synopsis
- * The typical incident involves a 25-year-old male perpetrator targeting a 13-year-old girl, often occurring on public roads during summer afternoons, showing patterns similar to sexual assault victim demographics.
- * Despite high recidivism rates and concerns about escalation to more serious crimes, reported incidents decreased significantly over the study period, prompting discussions about offender treatment and prevention strategies.
Disturbances in the fatty acid lipidome are increasingly recognized as key drivers in the progression of various brain disorders. In this review article, we delve into the impact of Δ9 fatty acid desaturases, with a particular focus on stearoyl-CoA desaturase-1 (SCD1), within the setting of neuroinflammation, neurodegeneration, and brain repair. Over the past years, it was established that inhibition or deficiency of SCD1 not only suppresses neuroinflammation but also protects against neurodegeneration in conditions such as multiple sclerosis, Alzheimer's disease, and Parkinson's disease.
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