Publications by authors named "J C Limpens"
Article Synopsis
- Obesity is linked to vitamin D deficiency, but previous studies on vitamin D supplementation's effects on weight have been inconsistent.
- This study aimed to review and analyze data from randomized clinical trials (RCTs) involving calcitriol (active vitamin D) to see its impact on body weight and related metrics.
- The analysis of 411 participants found that calcitriol supplementation does not significantly affect body weight or other weight-related measures compared to a placebo group.
Limited sensitivity of permafrost soils to heavy rainfall across Svalbard ecosystems.
Sci Total Environ
September 2024
Together with warming air temperatures, Arctic ecosystems are expected to experience increases in heavy rainfall events. Recent studies report accelerated degradation of permafrost under heavy rainfall, which could put significant amounts of soil carbon and infrastructure at risk. However, controlled experimental evidence of rainfall effects on permafrost thaw is scarce.
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- The study evaluates the effectiveness of first-trimester versus second-trimester prenatal ultrasounds in detecting fetal structural anomalies in low-risk pregnant women.
- It compares the accuracy of a single second-trimester scan to a combination of first- and second-trimester scans in identifying these anomalies before 24 weeks of gestation.
- Methodology included a comprehensive literature search and analysis of various studies, with findings based on a meta-analysis of results from 87 studies involving over 7 million fetuses.
Article Synopsis
- Prenatal factors like maternal stress, infection, and nutrition can influence fetal brain development and potentially increase the risk of dementia later in life, prompting a systematic review of existing studies.
- A total of 68 studies were analyzed, focusing on factors like maternal and paternal age, birth order, season of birth, and prenatal exposures, with results indicating that less optimal birth environments correlated with higher dementia risk.
- The review concluded that certain prenatal factors, particularly those linked to unfavorable environments, are associated with increased dementia risk, and highlighted the need for further research to clarify causal relationships while considering confounding factors like socioeconomic status.
Article Synopsis
- - Hyperemesis gravidarum (HG) is a severe pregnancy condition resulting in intense nausea and vomiting, which can cause undernutrition and poor maternal weight gain, potentially leading to adverse outcomes for the baby.
- - A systematic review of 61 studies involving over 20 million participants found that HG significantly raises the risks of preterm birth, low birth weight, the need for neonatal resuscitation, NICU admission, and placental abruption.
- - The study also indicated that HG is associated with lower instances of very high birth weights (>4000g) and stillbirths, suggesting a complex relationship between HG and various perinatal outcomes.