Publications by authors named "J C Lerman"
Article Synopsis
- The PARACOR-19 trial investigated whether the medication sacubitril/valsartan could improve heart health markers in patients who had recently recovered from COVID-19.
- In this study involving 42 participants, the drug did not significantly affect the primary cardiac injury markers, high-sensitivity cardiac troponin T and soluble ST2, compared to a placebo.
- However, exploratory results showed that sacubitril/valsartan led to notable reductions in other heart-related biomarkers, indicating it might help in reducing cardiac stress and improving collagen turnover.
Background: Heart transplant (HT) in recipients with left ventricular assist devices (LVADs) is associated with poor early post-HT outcomes, including primary graft dysfunction (PGD). As complicated heart explants in recipients with LVADs may produce longer ischemic times, innovations in donor heart preservation may yield improved post-HT outcomes. The SherpaPak Cardiac Transport System is an organ preservation technology that maintains donor heart temperatures between 4 °C and 8 °C, which may minimize ischemic and cold-induced graft injuries.
View Article and Find Full Text PDFIntroduction: Constriction band syndrome (CBS) is a congenital limb anomaly frequently associated with clubfoot. Clubfeet in CBS patients may be associated with peroneal nerve dysfunction in the involved lower extremity; however, the etiology of this neuromuscular dysfunction is not clear. We sought to characterize the distribution of constriction bands on lower extremities with clubfoot and determine if neuromuscular deficit (NMD), defined here as having absent ankle dorsiflexion, was associated with ipsilateral proximal bands.
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