Assessment of posterior capsule integrity in posterior polar cataracts using anterior segment OCT.

Background: Posterior polar cataracts (PPC) pose a great surgical challenge to ophthalmic surgeons. Main intraoperative surgical concerns are increased risk of posterior capsular rupture (PCR), vitreous loss, and nuclear drop. Traditional assessment of posterior capsule integrity utilizing anterior segment- optical coherence tomography (AS-OCT) requires training, and it is a time-consuming process.

Identification of some dietary flavonoids as potential inhibitors of TMPRSS2 through protein-ligand interaction studies and binding free energy calculations.

Unlabelled: The continuing threat of COVID-19 and deaths need an urgent cost-effective pharmacological approach. Here, we examine the inhibitory activity of a group of dietary bioactive flavonoids against the human protease TMPRSS2, which plays a major role in SARS CoV-2 viral entry. After the molecular docking studies of a large number of flavonoids, four compounds with high binding scores were selected and studied in detail.

A Case-Control Study to Evaluate Candidal Parameters in the Oral Cavity of Patients with Type 2 Diabetes Mellitus.

Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus (DM).

Materials And Methods: The samples included in the study were divided into two groups: group A, comprises 50 patients with type 2 DM, and group B, comprises 30 subjects who were nondiabetic. A nonrandom consecutive sampling technique was used to enroll the subjects for the study.

Analytical and Bioanalytical Techniques for the Quantification of the Calcium Channel Blocker - Amlodipine: A Critical Review.

Hypertension is a condition in which blood pressure is elevated to an extent where benefit is obtained from blood pressure lowering. The risk of complications is proportional to the level that blood pressure raises. Calcium channel blockers are a class of compounds used in the treatment of hypertension.

Linezolid-A Review of Analytical Methods in Pharmaceuticals and Biological Matrices.

Bacterial resistance to antibiotics is a growing phenomenon in the world. Considering the relevance of antimicrobials for population and the reduction in the registration of new antimicrobials by regulatory agencies, proper quality control is required to minimize the spread of bacterial resistance and ensure the effectiveness of a treatment, as well as safety for the patient. The recent addition to the antimicrobial world is the oxazolidinone classes of antibiotics, especially useful to treat infections caused by Gram-positive bacteria.