RANK IVVY motif plays crucial roles in osteoclastogenesis.

RANKL and its receptor RANK play a vital role in osteoclastogenesis. RANK primarily recruits TRAFs to promote osteoclastogenesis but also contains an TRAF-independent motif (IVVY), which mediates osteoclast lineage commitment in vitro. Here, we have developed knockin mice in which inactivating mutations are introduced in the IVVY motif (IVVY to IVAF).

4D Optical fibers based on shape-memory polymers.

Adaptative objects based on shape-memory materials are expected to significantly impact numerous technological sectors including optics and photonics. In this work, we demonstrate the manufacturing of shape-memory optical fibers from the thermal stretching of additively manufactured preforms. First, we show how standard commercially-available thermoplastics can be used to produce long continuously-structured microfilaments with shape-memory abilities.

Co-drawing of technical and high-performance thermoplastics with glasses via the molten core method.

Among the different fundamental aspects that govern the design and development of elongated multimaterial structures via the preform-to-fiber technique, material association methodologies hold a crucial role. They greatly impact the number, complexity and possible combinations of functions that can be integrated within single fibers, thus defining their applicability. In this work, a co-drawing strategy to produce monofilament microfibers from unique glass-polymer associations is investigated.

Physicochemical Properties and Fiber-Drawing Ability of Tellurite Glasses in the TeO-ZnO-YO Ternary System.

Glasses in the TeO-ZnO-YO (TZY) ternary system are examined in the present work. The vitrification domain of the chosen oxide matrix is determined and differential scanning calorimetry as well as X-ray diffraction measurements are carried out. The material characterizations reveal that YO incorporation cannot exceed 5 mol.