Publications by authors named "J C Jaime-Perez"
Objectives: The main objective was to investigate the incidence of transfusion-associated graft-versus-host disease (TA-GVHD) in patients who underwent haploidentical hematopoietic cell transplants (HCT) and received non-irradiated leukoreduced blood components. The secondary objective was to describe our leukodepletion results in blood products obtained by the filters employed at our center.
Study Design And Methods: Clinical records from 2018 to 2023 were retrospectively analyzed, along with a prospective evaluation of residual leukocytes in blood components from June to November 2023 in order to confirm effectivity of our leukodepletion method.
A comparison of haploidentical versus HLA-identical sibling outpatient hematopoietic cell transplantation using reduced intensity conditioning in patients with acute leukemia.
Front Immunol
October 2024
Article Synopsis
- * A study of 121 patients with acute myeloblastic (AML) and acute lymphoblastic leukemia (ALL) revealed no significant differences in complete chimerism between haploidentical and HLA-identical transplants, though haploidentical HCT experienced more post-transplant complications.
- * After two years, overall survival rates were 60.6% for HLA-identical and 46.9% for haploidentical HCT, with measurable residual disease (MRD) at 30 and 100
: The lactate/pyruvate (LP) ratio has been studied as an alternative to serum lactate to determine clinical prognosis. Despite its clinical utility, there is a paucity of evidence evaluating the role of the L/P ratio in patients with sepsis. : We assessed the clinical utility of the L/P ratio in patients with sepsis.
View Article and Find Full Text PDFCorrigendum to "Outpatient ATG-free hematopoietic transplantation for severe aplastic anemia in limited-resource environments offers excellent results: Data from a single LATAM center" [Blood Cells, Mol. Dis. 109 (2024) 102885].
Blood Cells Mol Dis
February 2025
Outpatient ATG-free hematopoietic transplantation for aplastic anemia in limited-resource environments offers excellent results: Data from a single LATAM center.
Blood Cells Mol Dis
November 2024
Objective: To document the results of outpatient hematopoietic stem cell transplantation (HSCT) from the peripheral blood (PB) of sibling donors without anti-thymocyte globulin (ATG) in the conditioning regimen.
Material And Methods: Patients from a low-income population with severe AA who received a PB, unmanipulated sibling HLA-identical HSCT between 2000 and 2020 at a single institution were studied. Survival was the primary outcome.