Publications by authors named "J C Hillier"
Land use change is crucial to addressing the existential threats of climate change and biodiversity loss while enhancing food security [M. Zurek , , 1416-1421 (2022)]. The interconnected and spatially varying nature of the impacts of land use change means that these challenges must be addressed simultaneously [H.
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- Cardiac surgery with cardiopulmonary bypass (CPB) can cause lung injuries, and this study evaluated the use of low frequency ventilation (LFV) during such procedures in patients needing valve surgery.
- A total of 63 patients participated, with primary outcomes focused on lung inflammation markers and secondary outcomes on lung function and mobility post-surgery.
- The results indicated that LFV was safe and effective, leading to better preserved lung function and movement, suggesting its potential for broader application in future studies.
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- Silicon quantum dots are being explored for spin qubit applications because of their strong intrinsic spin-orbit coupling, which influences hole-spin dynamics.
- The study demonstrates a singlet-triplet qubit using hole states in a metal-oxide-semiconductor double quantum dot, achieving rapid control with oscillations up to 400 MHz and a maximum coherence time of 1.3 μs.
- This research identifies ways to enhance qubit performance and lays the groundwork for scaling up to larger arrays of qubits in two-dimensional configurations.
The Wnt receptor Frizzled3 (FZD3) is important for brain axonal development and cancer progression. We report structures of FZD3 in complex with extracellular and intracellular binding nanobodies (Nb). The crystal structure of Nb8 in complex with the FZD3 cysteine-rich domain (CRD) reveals that the nanobody binds at the base of the lipid-binding groove and can compete with Wnt5a.
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