Publications by authors named "J C Hamilton"

Periprosthetic joint infection (PJI) is a leading cause and major complication of joint replacement failure. As opposed to standard-of-care systemic antibiotic prophylaxis for PJI, we developed and tested titanium femoral intramedullary implants with titania nanotubes (TNTs) coated with the antibiotic gentamicin and slow-release agent chitosan through electrophoretic deposition (EPD) in a mouse model of PJI. We hypothesized that these implants would enable local gentamicin delivery to the implant surface and surgical site, effectively preventing bacterial colonization.

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Article Synopsis
  • The study compares the effects of a non-antibiotic treatment (intrauterine dextrose) versus systemic antibiotics (ceftiofur) on the vaginal microbiome of dairy cows with clinical metritis around 7 days post-calving.
  • Results indicated that both treatments resulted in only minor differences in the microbiome, suggesting that dextrose could be a viable alternative to antibiotics.
  • The study found no significant changes in alpha or beta diversity of the microbiome among the two treatments at various time points.
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is a globally significant genus of plant pathogens known for causing anthracnose across a diverse array of hosts. Notably, is a pathogen affecting maize. Annually, the global economic impact of this pathogen reaches billions of US dollars.

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Dynamical symmetries, time-dependent operators that almost commute with the Hamiltonian, extend the role of ordinary symmetries. Motivated by progress in quantum technologies, we illustrate a practical algebraic approach to computing such time-dependent operators. Explicitly we expand them as a linear combination of time-independent operators with time-dependent coefficients.

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