Publications by authors named "J C Gomez-Esteban"
Introduction: Falls are a common and debilitating complication in Parkinson's disease (PD). Previous studies have primarily focused on cohorts with prevalent falls or advanced disease stages. This study assessed risk factors for falls in early-stage falls-naïve cohort stratified by sex.
View Article and Find Full Text PDFIntroduction: In Parkinson's Disease (PD), despite available treatments focusing on symptom alleviation, the effectiveness of conventional therapies decreases over time. This study aims to enhance the identification of candidates for device-aided therapies (DAT) using artificial intelligence (AI), addressing the need for improved treatment selection in advanced PD stages.
Methods: This national, multicenter, cross-sectional, observational study involved 1086 PD patients across Spain.
Unlabelled: Parkinson's disease (PD) is characterized by motor and non-motor symptoms. Nutritional alterations are one of the non-motor symptoms that most influence the quality of life (QoL) in PD.
Objective: Therefore, this review aims to evaluate whether nutritional alterations are related either to the severity of motor and non-motor symptoms through the gut-brain axis or to the different treatments for PD and whether all of this, in turn, impacts the QoL of patients.
Virtual Coaching for Home Rehabilitation - Evidence of an Empirical Study.
Stud Health Technol Inform
August 2024
Older individuals often face disabilities or diseases that lower their quality of life (QoL). While inpatient rehabilitation can initially enhance QoL, there is often a lack of continuation at home. Virtual coaches (VCs) as specific embodied conversational agents promise appropriate support for home rehabilitation.
View Article and Find Full Text PDFArticle Synopsis
- The study investigates protein-rich inclusions in neurodegeneration, noting that current iPSC models lack reproducibility and speed in developing these inclusions.
- Researchers created new iPSC models that allow for rapid production of CNS cells with proteins prone to aggregation, enabling the tracking of inclusions at a single level.
- They identified various inclusion types with differing effects on neuron survival and isolated proteins that could influence toxicity, paving the way for improved drug development for neurodegenerative diseases.