Publications by authors named "J C Gana"

Objective: Nonalcoholic Fatty Pancreas Disease (NAFPD) is characterized by excessive lipid accumulation within the pancreas in the absence of alcohol intake, potentially leading to pancreatic dysfunction and metabolic complications, including type 2 diabetes mellitus, acute and chronic pancreatitis, and pancreatic carcinoma. The authors aim to estimate the prevalence of NAFPD and its association with anthropometric parameters in a cohort of Chilean adolescents.

Method: The authors conducted a cross-sectional analysis of the "Growth and Obesity Chilean Cohort Study" (GOCS), a longitudinal study involving nearly 1000 children, followed yearly since 2006.

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Gene variants in the gene are strongly associated with circulating bilirubin levels in several populations, as well as other variants of modest effect across the genome. However, the effects of such variants are unknown regarding the Native American ancestry of the admixed Latino population. Our objective was to assess the Native American genetic determinants of serum bilirubin in Chilean admixed adolescents using the local ancestry deconvolution approach.

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Unlabelled: Hypertriglyceridemia (HTG)-induced acute pancreatitis (AP) secondary to insulin deficiency following the onset of type 1 diabetes mellitus (T1DM) is a rare but serious complication in children.

Objective: To describe the diagnosis and treatment of severe HTG and to emphasize the need for timely diagnosis of T1DM.

Clinical Case: A 15-year-old female adolescent with a history of overweight presented with a two-weeks history of fever, anorexia, and diffuse abdominal pain.

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Article Synopsis
  • The study analyzed 60 bacterial isolates from the beef production chain in Gauteng, South Africa, using whole-genome sequencing and bioinformatics to determine their genomic characteristics.
  • Researchers identified seven sequence types (STs) and six clonal complexes (CCs), revealing that ST204 and CC204 were the most prevalent among the samples.
  • The investigation uncovered 44 virulence factors, two antimicrobial resistance (AMR) genes, and highlighted that certain genes associated with virulence and resistance were present across all isolates, indicating potential therapeutic concerns for these pathogens.
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