Publications by authors named "J C Erdozain"
Objectives: To determine the potential predictive value in patients with systemic lupus erythematous of the ankle-brachial index (ABI) for the occurrence of arterial vascular events.
Methods: 216 lupus patients from a prospective clinical cohort were evaluated using the ABI at the start of the study and then followed up for 5 years. Abnormal ABI was defined as an index ≤0.
Restrictive Use of Oral Glucocorticoids in Systemic Lupus Erythematosus and Prevention of Damage Without Worsening Long-Term Disease Control: An Observational Study.
Arthritis Care Res (Hoboken)
April 2018
Objective: To analyze the influence of 2 different treatment strategies on general and specific damage accrual in patients with systemic lupus erythematosus (SLE).
Methods: Two cohorts were identified according to the responsible physicians: patients treated at the autoimmune diseases unit (ADU), and patients treated by other members of the internal medicine (IM) department. Members of the ADU worked with a protocol including the universal prescription of hydroxychloroquine (HCQ), the use of maximum oral prednisone dosages ≤30 mg/day and maintenance therapy with ≤5 mg/day, by using methylprednisolone pulses and/or early immunosuppressive (IS) drugs.
Article Synopsis
- The study analyzes how risk factors for peripheral artery disease (PAD) differ by age in patients with systemic lupus erythematosus (SLE).
- 216 SLE patients were divided into three age groups, and various risk factors were identified through statistical analysis.
- Results showed that younger patients had risk factors like antiphospholipid antibodies and glucocorticoids, while older patients showed trends related to hypertension and hypercholesterolemia, indicating that age influences PAD risk factors.