Publications by authors named "J C Ejike"

Background: The Abdominal Compartment Society (WSACS) established consensus definitions and recommendations for the management of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) in 2006, and they were last updated in 2013. The WSACS conducted an international survey between 2022 and 2023 to seek the agreement of healthcare practitioners (HCPs) worldwide on current and new candidate statements that may be used for future guidelines.

Methods: A self-administered, online cross-sectional survey was conducted under the auspices of the WSACS to assess the level of agreement among HCPs over current and new candidate statements.

View Article and Find Full Text PDF

Genetically encoded sensors enable quantitative imaging of analytes in live cells. Sensors are commonly constructed by combining ligand-binding domains with one or more sensitized fluorescent protein (FP) domains. Sensors based on a single FP can be susceptible to artifacts caused by changes in sensor levels or distribution in vivo.

View Article and Find Full Text PDF

Introduction: The Uganda Ministry of Health recommends facility- and community-based differentiated antiretroviral therapy (DART) models to support person-centred care for eligible clients receiving antiretroviral therapy (ART). Healthcare workers assess client eligibility for one of six DART models upon initial enrolment; however, client circumstances evolve, and their preferences are not routinely adjusted. We developed a tool to understand the proportion of clients accessing preferred DART models and compared the outcomes of clients accessing preferred DART models to the outcomes of clients not receiving preferred DART models.

View Article and Find Full Text PDF

Plasmodesmata (PD) facilitate movement of molecules between plant cells. Regulation of this movement is still not understood. Plasmodesmata are hard to study, being deeply embedded within cell walls and incorporating several membrane types.

View Article and Find Full Text PDF
Article Synopsis
  • The review investigates the link between fluid administration and intra-abdominal pressure (IAP) in patients at risk of intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS).
  • A comprehensive literature search uncovered various studies indicating that fluid resuscitation often exacerbates IAH, creating a cyclical problem where patients require even more fluids for management.
  • While the timing and strategy for fluid management are critical, there is a lack of clear guidelines, and in severe cases, surgical intervention may be necessary to prevent serious complications.
View Article and Find Full Text PDF