Publications by authors named "J C Eggers"

Despite the fundamental role of bacterial strain variation in gut microbiota function, the number of unique strains of a species that can stably colonize the human intestine is still unknown for almost all species. Here we determine the strain richness (SR) of common gut species using thousands of sequenced bacterial isolates with paired metagenomes. We show that SR varies across species, is transferable by faecal microbiota transplantation, and is uniquely low in the gut compared with soil and lake environments.

View Article and Find Full Text PDF
Article Synopsis
  • Land use intensification is putting pressure on protected areas, especially nonforested rangelands, which comprise about 40% of these areas and face issues like overgrazing and land conversion.
  • A study in the southern Caucasus assessed the effectiveness of 52 protected areas in mitigating land-use pressures and found that, overall, these areas failed to prevent green vegetation loss, with losses being greater inside protected zones in most countries.
  • The study revealed that livestock overgrazing is a major driver of the ineffectiveness, particularly in multiple-use protected areas, and emphasizes the need for better integration of conservation efforts that consider nonforest ecosystems.
View Article and Find Full Text PDF

Alterations to the gut microbiome and exposure to metals during pregnancy have been suggested to impact inflammatory bowel disease. Nonetheless, how prenatal exposure to metals eventually results in long-term effects on the gut microbiome, leading to subclinical intestinal inflammation, particularly during late childhood, has not been studied. It is also unknown whether such an interactive effect drives a specific subgroup of children toward elevated susceptibility to intestinal inflammation.

View Article and Find Full Text PDF