Publications by authors named "J C Dujardin"

Leishmania is a genus of the family Trypanosomatidae that unites obligatory parasitic flagellates causing a variety of vector-borne diseases collectively called leishmaniasis. The symptoms range from relatively innocuous skin lesions to complete failures of visceral organs. The disease is exacerbated if a parasite harbors Leishmania RNA viruses (LRVs) of the family Pseudototiviridae.

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Article Synopsis
  • The Neotropical realm is a highly biodiverse region with significant public health risks due to zoonoses, particularly zoonotic leishmaniasis caused by Leishmania (Viannia) braziliensis.
  • This study represents the first genome-wide analysis of 257 Leishmania isolates across Latin America, revealing extensive genetic variability among populations associated with different environments.
  • Two major parasite groups were identified, one linked to the Amazon and the other to the Atlantic Forest, each showing distinct genetic profiles and eco-epidemiological characteristics.
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  • The study investigates the morphological variation in sensilla shapes of a dominant chigger species in Southeast Asia, focusing on their potential role as carriers of scrub typhus.
  • Sensilla, specialized sensory structures, were found in two distinct forms (round and ovoid) regardless of local conditions or hosts, prompting questions about species heterogeneity.
  • Despite using genetic and morphometric techniques to analyze the two forms, the research found no genetic or morphological evidence to suggest that these variations indicate different species within this chigger population.
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We sequenced Leishmania donovani genomes in blood samples collected in emerging foci of visceral leishmaniasis in western Nepal. We detected lineages very different from the preelimination main parasite population, including a new lineage and a rare one previously reported in eastern Nepal. Our findings underscore the need for genomic surveillance.

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Fly identification is the primary step of analysis in forensic entomology. Although morphology and molecular techniques are considered satisfactory methods, some constraints may arise from a financial or even human point of view. Over the past decade, the geometric morphometric approach has been increasingly advocated for the classification and identification of arthropods.

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