Publications by authors named "J C Delaleu"
Article Synopsis
- - Pancreatic cancer is a leading cause of cancer-related deaths in the U.S., with a notably low 5-year survival rate of just 11%, and cryoablation is being explored as a promising treatment option for both locally advanced and metastatic cases.
- - A case study discusses a 47-year-old woman with pancreatic cancer who underwent multiple treatments including a Whipple procedure, chemotherapy, and ultimately, palliative cryoablation for symptom relief.
- - Post-cryoablation, the patient developed rare disseminated intravascular coagulation (DIC), leading to severe complications despite treatments, including multiple blood transfusions and intensive care management, indicating the risks associated with this emerging therapy.
Neutrophilic dermatoses are a group of inflammatory skin conditions characterized by a neutrophilic infiltrate on histopathology with no evidence of infection. These conditions present with a wide range of clinical manifestations, including pustules, bullae, abscesses, papules, nodules, plaques, and ulcers. The classification of neutrophilic dermatoses is based on the localization of neutrophils in the skin.
View Article and Find Full Text PDFTissue immunity and responses to injury depend on the coordinated action and communication among physiological systems. Here, we show that, upon injury, adaptive responses to the microbiota directly promote sensory neuron regeneration. At homeostasis, tissue-resident commensal-specific T cells colocalize with sensory nerve fibers within the dermis, express a transcriptional program associated with neuronal interaction and repair, and promote axon growth and local nerve regeneration following injury.
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