Publications by authors named "J C Debes"

Background: Cholangiocarcinoma (CCA) represents a global health challenge, with rising incidence and mortality rates. This study aimed to elucidate the clinical course and practices of CCA in Latin America.

Methods: This observational cohort study investigated individuals diagnosed with CCA between 2010 and 2023 at five referral centres across Latin America.

View Article and Find Full Text PDF

Sub-Saharan Africa has a high burden of hepatitis B virus (HBV) and hepatocellular carcinoma (HCC). The lack of surveillance programs has led to low rates of diagnosis and treatment, particularly in rural areas. We conducted mobile HBV-HCC screening clinics in rural Tanzania between March 2021 and February 2023.

View Article and Find Full Text PDF
Article Synopsis
  • - The study examined how palliative care, race, and socioeconomic status affect the use of invasive procedures in patients with hepatocellular carcinoma (HCC), using data from hospitalizations between 2016 and 2019.
  • - Results showed that 18.1% of HCC hospitalizations involved palliative care, which was linked to fewer invasive procedures in terminal cases, while Black and Hispanic patients were more likely to undergo aggressive treatments compared to white patients.
  • - Palliative care not only led to less aggressive end-of-life care but also resulted in lower hospitalization costs for both terminal and nonterminal cases, highlighting its importance in managing HCC patients.
View Article and Find Full Text PDF

Hepatocellular carcinoma (HCC) is one of the most common causes of cancer-related mortality. This particular type of cancer has the distinctive characteristic of mostly happening in individuals with an underlying liver disease. This makes the management of patients more challenging, since physicians must take into consideration two different conditions, the chronic liver disease and the tumor.

View Article and Find Full Text PDF