Publications by authors named "J C Daubert"

Introduction: Individuals with end-stage kidney disease (ESKD) maintained on hemodialysis (HD) carry a high risk of cardiac arrhythmias. This risk is heightened by episodic hyperkalemia. The purpose of the study was to investigate whether patiromer administered daily reduced episodes of hyperkalemia in those with ESKD who receive HD, and to explore whether prescription of patiromer reduced the number of significant arrhythmia events.

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Importance: The emergence of novel programming guidelines that reduce premature and inappropriate therapies along with the availability of new implantable cardioverter-defibrillator (ICD) technologies lacking traditional endocardial antitachycardia pacing (ATP) capabilities requires the reevaluation of ATP as a first strategy in terminating fast ventricular tachycardias (VTs) in primary prevention ICD recipients.

Objective: To assess the role of ATP in terminating fast VTs in primary prevention ICD recipients with contemporary programming.

Design, Setting, And Participants: This global, prospective, double-blind, randomized clinical trial had an equivalence design with a relative margin of 35%.

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Aims: The detailed sub-categories of death and hospitalization, and the impact of comorbidities on cause-specific outcomes, remain poorly understood in heart failure (HF) with preserved ejection fraction (HFpEF). We sought to evaluate rates and predictors of cardiovascular (CV) and non-CV outcomes in HFpEF.

Methods: The Karolinska-Rennes study was a bi-national prospective observational study designed to characterize HFpEF (ejection fraction ≥45%).

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Article Synopsis
  • A study at Duke University Hospital reviewed 421 patients with left ventricular assist devices (LVADs) and implantable cardioverter-defibrillators (ICDs) to assess the frequency and causes of ICD shocks post-surgery.
  • Out of these patients, 33.9% experienced at least one shock, with 77.3% deemed appropriate and 22.7% inappropriate, primarily due to supraventricular tachycardia.
  • The findings suggest that better ICD programming, such as longer detection delays and higher rate cutoffs, could reduce the number of inappropriate shocks in LVAD recipients.
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  • A study was conducted to compare changes in brain imaging and cognitive function between atrial fibrillation (AF) patients treated with catheter ablation and those receiving medical therapy.
  • The research involved 12 patients undergoing ablation and 11 on medical management, assessing white matter hyperintensity burden (WMHb) and cortical thickness over 6 weeks and 1 year.
  • Findings showed that patients who underwent ablation had less cortical thinning in areas linked to Alzheimer's risk compared to those on medical therapy, highlighting the potential impact of AF treatment on cognitive health.
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