Publications by authors named "J C Cone"
Conversion of Lignocellulosic Biomass Into Valuable Feed for Ruminants Using White Rot Fungi.
J Anim Physiol Anim Nutr (Berl)
January 2025
White rot fungi can degrade lignin and improve the nutritional value of highly lignified biomass for ruminants. We screened for excellent fungi-biomass combinations by investigating the improvement of digestibility of wheat straw, barley straw, oat straw, rapeseed straw, miscanthus, new reed, spent reed from thatched roofs, and cocoa shells after colonisation by Ceriporiopsis subvermispora (CS), Lentinula edodes (LE), and Pleurotus eryngii (PE) (indicated by increased in vitro gas production [IVGP]). First, growth was evaluated for three fungi on all types of biomass, over a period of 17 days in race tubes.
View Article and Find Full Text PDFThe aim of fungal treatment of organic matter for ruminants is the improvement of its degradability. So far, such treatment appears to be time-consuming and improvement has been modest. In previous work, we observed within three white rot species that there is modest () or low ( and ) variation in fiber degradation in wheat straw during seven weeks of incubation.
View Article and Find Full Text PDFChronic and Acute Pain and Adverse Economic Outcomes in a 9/11-Exposed Cohort.
Int J Environ Res Public Health
November 2024
Article Synopsis
- A study examined the impact of acute and chronic pain on economic and quality-of-life outcomes using data from the World Trade Center Health Registry during 2020-2021.
- The findings revealed that individuals with severe pain experienced significantly higher odds of early retirement (3.12 times), low household income (5.34 times), income decline (2.56 times), and poor health days (14.4 times) compared to those without pain.
- The results suggest that both acute and chronic pain can have lasting negative effects on a person's financial stability and overall well-being long after the initial diagnosis.
Article Synopsis
- Tarperprumig (ALXN1820) is a bispecific antibody designed to treat conditions caused by dysregulated activity in the complement alternative pathway, usable via small volume injections either under the skin or intravenously.
- It consists of two variable domains that target properdin and human serum albumin, showing a high binding affinity and forming a stable complex.
- The antibody effectively inhibits key processes related to complement pathway activation and is currently undergoing clinical development for relevant disorders.
Introduction: There are well-documented racial and ethnic disparities in mortality after cancer in the general population, but less is known about whether disparities also exist in disaster-exposed populations.
Methods: We conducted a longitudinal cohort study of 4341 enrollees in the World Trade Center Health Registry (WTCHR) with a first-ever primary invasive cancer diagnosis after 9/11/2001 and followed through 2020. We examined associations of race and ethnicity with all-cause mortality risk and cause-specific mortality risk using multivariable Cox proportional hazards regression models and Fine and Gray's proportional sub-distribution hazards models, respectively.