Immune Response to the Recombinant Apa Protein from Mycobacterium tuberculosis Expressed in Streptomyces lividans After Intranasal Administration in Mice. Induction of Protective Response to Tubercle Bacillus Aerosols Exposure.

Identifying and evaluating potential vaccine candidates has become one of the main objectives to combat tuberculosis. Among them, mannosylated Apa antigen from Mycobacterium tuberculosis and the non-mannosylated protein expressed in Escherichia coli, have been studied. Although both proteins can induce a protective response in mice, it has been considered that native protein can be dispensed.

Homicide in children under ten years old in México: A 20-year study.

Background: In a society, children are the most vulnerable members of the population. Violence experienced in Mexico during the last decade has also affected children under ten years of age.

Objective: Analyze the trend of homicides in children under ten years from 1998 to 2017.

Safety of laparoscopic cholecystectomy in patients older than 90 years in a private hospital in Ecuador: A case series.

Antecedentes: La tasa de litiasis biliar y sus complicaciones son mayores en los ancianos. Algunos autores describen la edad como un factor principal que aumenta significativamente la morbilidad y la mortalidad de los pacientes sometidos a colecistectomía.

Objetivo: Describir la seguridad de la colecistectomía laparoscópica centrándose en su tasa de complicaciones y de conversión en pacientes mayores de 90 años, en un hospital privado de un país en desarrollo.

Prostate cancer mortality according to marginalization status in Mexican states from 1980 to 2013.

Objective: To assess prostate cancer (PC) mortality in Mexico from 1980 to 2013, according to the state marginalization level.

Materials And Methods: Using age-adjusted rates in men ≥ 40 years old, we estimated trends and age-cohort-period effects of PC mortality from 1980-2013 according to state marginalization status by using a joinpoint regression model and a Poisson regression model proposed by Holford.

Results: The PC mortality risk has increased nationwide at a constant rate (2% annually) during the past 13 years.