Publications by authors named "J C Bousquet"
Forests face an escalating threat from the increasing frequency of extreme drought events driven by climate change. To address this challenge, it is crucial to understand how widely distributed species of economic or ecological importance may respond to drought stress. In this study, we examined the transcriptome of white spruce (Picea glauca (Moench) Voss) to identify key genes and metabolic pathways involved in the species' response to water stress.
View Article and Find Full Text PDFBackground: Allergic rhinitis (AR) is a highly prevalent disease. We aimed to assess the symptoms that physicians who see patients with AR perceive as the most bothersome in their patients.
Methods: We performed a cross-sectional study based on an online questionnaire sent to all members of the Allergic Rhinitis and its Impact on Asthma (ARIA) initiative.
Objective: The evaluation of health benefits and harms of an intervention with GRADE Evidence to Decision (EtD) frameworks includes judgments if the effects are "trivial", "small", "moderate" or "large". Such judgments ideally require the a priori establishment of decision thresholds (DTs), whose empirical derivation for single outcomes has been previously described. In this article, we provide a methodological approach to estimate DTs for composite endpoints based on disutilities.
View Article and Find Full Text PDFBackground: Allergic rhinitis (AR) affects up to 40% of the pediatric population. The US practice parameter recommends the use of INAH or INCS as first-line therapy for the treatment of AR. Although not directly targeted to children, the recent US Practice Parameters proposed intranasal antihistamines as first-line therapy whereas the ARIA guidelines did not.
View Article and Find Full Text PDFArticle Synopsis
- A study involving 505 adult asthma patients from Belgium examined the relationship between detailed asthma symptoms reported by patients and their lung function and inflammation levels.
- Key symptoms analyzed included cough, dyspnea, wheezing, chest tightness, and airway secretion, measured on a five-point scale, revealing several demographic and health-related factors influencing these symptoms.
- The findings suggest that individualized treatment for asthma could be developed based on the specific symptoms and their associations with various demographic and health indicators.