Publications by authors named "J C BARNETT"
Article Synopsis
- Arthritis causes bone damage due to an imbalance in cellular activity between osteoclasts (bone-resorbing cells) and osteoblasts (bone-building cells).
- The small molecule ELP-004 primarily inhibits TRPC channels, which affects osteoclast maturation when driven by inflammatory factors like TNFα or LTB4.
- ELP-004 shows potential in reducing bone erosion in a mouse model of rheumatoid arthritis, highlighting TRPC channels as significant players in inflammatory bone damage and positioning ELP-004 as a promising therapeutic candidate.
There is a crucial need to more deeply understand the impact and etiology of bias toward persons with developmental disabilities (PWDD). A largely unstudied area of concern and possible intervention is the portrayal of PWDD in medical education. Often, medical photographs portray PWDD with obscured faces, emotionless, and posed in an undignified way.
View Article and Find Full Text PDFFour new and one previously reported silver 4,4'-vinylenedipyridine (Vpe) coordination polymers were tested as anion exchange materials to assess their potential for pollutant sequestration and compared to analogous silver 4,4'-bipyridine (bipy) coordination polymers. The materials were synthesized using nitrate, tetrafluoroborate, perchlorate, perrhenate, or chromate as the anion to produce cationic coordination polymers with solubilities ranging from 0.0137(7) to 0.
View Article and Find Full Text PDFMeralgia Paresthetica: An Anatomical Review and Surgical Case Presentation Utilizing a Robotic Exoscope.
Plast Reconstr Surg Glob Open
December 2024
Background: Meralgia paresthetica (MP) is a neuropathic condition marked by pain, tingling, and numbness in the anterolateral thigh, primarily caused by compression of the lateral femoral cutaneous nerve (LFCN). Although compression often occurs beneath the inguinal ligament, anatomical variations can lead to different entrapment sites. Treatments range from conservative measures to surgical decompression, depending on symptom severity.
View Article and Find Full Text PDFIntroduction: The aim of this trial was to investigate the impact of early thoracic and shoulder girdle exercises on chronic pain and Health-Related Quality of Life in patients with blunt chest wall trauma, when compared to normal care.
Methods: A multi-centre, parallel, randomised controlled trial, in which adult patients presenting to hospital with blunt chest wall trauma were allocated to either control or intervention group. The intervention was an exercise programme consisting of four simple thoracic and shoulder girdle exercises, completed for one week.