Publications by authors named "J C Angelillo"

Article Synopsis
  • * In experiments using mouse models, the absence of MHC class II in LECs led to reduced tumor growth and enhanced responses from effector T-cells, indicating an important local role for LECs in maintaining Treg suppressive functions within tumors.
  • * The study highlights that MHC class II-restricted antigen presentation by LECs is crucial for regulating Tregs locally in the tumor environment, acting as a barrier against effective T-cell-mediated immune responses.
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In an attempt to determine the role that nondepolarizing neuromuscular blocking agents play in the intraoperative position of the mandibular condyle, occlusal checkbites were taken on 10 patients under general anesthesia before and after neuromuscular blockade with vecuronium. These checkbites were compared to checkbites taken preoperatively. Nondepolarizing neuromuscular blocking agents had no effect on condylar position recordings during general anesthesia.

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Ankylosing spondylitis is a disease process that causes inflammatory changes of the involved joints. Often the first clinical indication of the condition is lumbosacral pain and discomfort with limited range of motion. Progressive synovial changes eventually involve all of the axial joints including the temporomandibular joint.

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A case of synovial chondromatosis of the temporomandibular joint with extracapsular extension is described. Temporomandibular joint magnetic resonance imaging proved invaluable in establishing a definitive diagnosis.

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Three anesthetic techniques were compared in this study: 1) Intermittent Brevital boluses supplemented with fentanyl and midazolam all titrated to patient movement, 2) constant infusion of Brevital supplemented with fentanyl and midazolam all delivered in calculated mg/kg doses based on total body weight, and 3) constant infusion of methohexital (Brevital) and alfentanil (Alfenta) supplemented by midazolam (Versed), droperidol, and glycopyrolate (Robinul) delivered in calculated mg/kg doses based on lean body mass. Nitrous oxide was delivered in all cases via nasal mask in a 30% to 50% concentration. The mean total dose of Brevital in group 1 (intermittent Brevital bolus) was 0.

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