Experimental chemotherapy in children with cancer--a parent's view.

Parental attitude and the parents' perceptions of a child's responsibilities were measured by mailing a questionnaire to 156 parents of cured children of the Pediatric Oncology Center, University of Groningen. Simplistically, the questionnaire concerned parental judgment on (1) the role of the child in decisions about experimental therapy, (2) what information should be related to the child and by whom, (3) parental attitudes toward experimental therapy, and (4) the parents' opinions about ethical aspects of proposing experimental therapy. A high response rate (87.

Methods for comparing groups of growth curves when patterns of observation times vary among subjects.

A variety of statistical techniques is available if growth is to be compared for two groups followed up over a certain period. In practice straightforward application of such techniques may be hampered if patterns of observation times vary among subjects. Different approaches to deal with such variation are illustrated by analysing data from infants (0-18 months) living in Lesotho, Southern Africa.