Publications by authors named "J C Abadie"

Article Synopsis
  • Tympanokeratomas (cholesteatomas) are harmful growths in the middle ear and are often surgically treated; this study focuses on using non-EP diffusion-weighted MRI for diagnosis in dogs.
  • The research involved analyzing 62 dog ears diagnosed with either tympanokeratomas or other types of otitis media, with non-EP DWI achieving a detection accuracy of 77.4% and ADC values ranging between 517 to 2447 mm/s.
  • A specific ADC cut-off value of 916 mm/s was found to effectively indicate tympanokeratomas, providing a combined 80.9% accuracy when considering both qualitative DWI images and ADC maps.
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Disorders of mitochondrial function are responsible for many inherited neuromuscular and metabolic diseases. Their combination of high mortality, multi-systemic involvement, and economic burden cause devastating effects on patients and their families. Molecular diagnostic tools are becoming increasingly important in providing earlier diagnoses and guiding more precise therapeutic treatments for patients suffering from mitochondrial disorders.

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Glioma is the most common primary brain tumor in dogs and predominantly affects brachycephalic breeds. Diagnosis relies on CT or MRI imaging, and the proposed treatments include surgical resection, chemotherapy, and radiotherapy depending on the tumor's location. Canine glioma from domestic dogs could be used as a more powerful model to study radiotherapy for human glioma than the murine model.

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Background: High-salt diets promote urine dilution and decrease urolithiasis risk.

Objective: Prospectively evaluate the safety of chronic high dietary salt intake (randomized controlled trial).

Animals: Twenty research colony neutered, healthy aged cats (11.

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