Front Biosci (Schol Ed)
March 2024
Disorders of mitochondrial function are responsible for many inherited neuromuscular and metabolic diseases. Their combination of high mortality, multi-systemic involvement, and economic burden cause devastating effects on patients and their families. Molecular diagnostic tools are becoming increasingly important in providing earlier diagnoses and guiding more precise therapeutic treatments for patients suffering from mitochondrial disorders.
View Article and Find Full Text PDFGlioma is the most common primary brain tumor in dogs and predominantly affects brachycephalic breeds. Diagnosis relies on CT or MRI imaging, and the proposed treatments include surgical resection, chemotherapy, and radiotherapy depending on the tumor's location. Canine glioma from domestic dogs could be used as a more powerful model to study radiotherapy for human glioma than the murine model.
View Article and Find Full Text PDFBackground: High-salt diets promote urine dilution and decrease urolithiasis risk.
Objective: Prospectively evaluate the safety of chronic high dietary salt intake (randomized controlled trial).
Animals: Twenty research colony neutered, healthy aged cats (11.