The study investigates a new imaging technique, multi-spectral cryo-fluorescence tomography (CFT), for tracking fluorescent perfluorocarbon (PFC) nanoemulsions in mice with inflammation models.
By injecting different fluorescent PFC nanoemulsions into mice and imaging them 24 hours later, researchers were able to see how well these tracers localized in various tissues.
The results show that CFT effectively identifies the distribution of PFC nanoemulsions, providing a high-resolution alternative for validating probe localization compared to traditional histological methods.
DNA is damaged through various exogenous sources (e.g., automobile exhaust, tobacco smoke, and processed foods), which can yield diverse C8-dG bulky aryl adducts.