Publications by authors named "J Busschaert"
Within the wheat starchy endosperm, the protein content increases biexponentially from the inner to outer endosperm. Here, we studied how this protein gradient is reflected in mill fractions using three cultivars (Claire, Apache, and Akteur) grown without and with N-fertilization (300 kg N ha). The increasing protein content in successive break fractions was shown to reflect the protein gradient within the starchy endosperm.
View Article and Find Full Text PDFBackground: As real-world data on risankizumab in patients with moderate to severe Crohn's disease (CD) are scarce, we evaluated its effectiveness and safety in multirefractory Belgian patients.
Methods: Data from consecutive adult CD patients who started risankizumab before April 2023 were retrospectively collected at 6 Belgian centers. Clinical remission and response were defined using the 2-component patient-reported outcome.
Article Synopsis
- Advanced therapies like biologics and small molecules have been approved for treating moderate-to-severe ulcerative colitis, but patients with isolated proctitis were often excluded from clinical trials, creating an evidence gap for this specific group.
- In a study of 167 patients with active ulcerative proctitis who had already failed conventional treatments, it was found that 36.3% achieved short-term steroid-free remission, with better outcomes for bionaive patients and those treated with vedolizumab.
- The results support the effectiveness and safety of advanced therapies for ulcerative proctitis, suggesting that future trials should include these patients to better understand treatment options.