Publications by authors named "J Burrello"
Extracellular vesicles (EVs) offer valuable diagnostic and prognostic insights for cardiovascular (CV) diseases, but the influence of age-related chronic inflammation ("inflammaging") and sex differences on EV profiles linked to CV risk remains unclear. This study aimed to use EV profiling to predict age and stratify patients by CV risk. We developed an EVaging index by analyzing surface antigen profiles of serum EVs from 625 participants, aged 20 to 94 years, across varying CV risk groups.
View Article and Find Full Text PDFManagement of Renovascular Hypertension and Renal Denervation in Patients with Hypertension: An Italian Nationwide Survey.
High Blood Press Cardiovasc Prev
September 2024
Introduction: Renovascular hypertension (RVH) remains underdiagnosed despite its significant cardiovascular and renal morbidity.
Aim: This survey investigated screening and management practices for RVH among hypertensive patients in Italian hypertension centres in a real-life setting. Secondary, we analysed the current spread of renal denervation (RDN) and the criteria used for its eligibility.
Article Synopsis
- Hyperkalemia is a common electrolyte imbalance, impacting around 7.3% of patients with hypertension, often due to medications or chronic kidney disease.
- A small percentage (0.04%) of these patients had familial hyperkalemic hypertension (FHH), with higher prevalence in those with unexplained hyperkalemia.
- Hyperkalemia is linked to increased cardiovascular risks, emphasizing the need for early diagnosis and tailored treatment strategies for effective management.
Article Synopsis
- Primary aldosteronism (PA) is a leading cause of high blood pressure, and the study aimed to assess the effectiveness of a new testing method (ADRR) for diagnosing PA compared to the traditional method (ARR).
- The research involved 1110 patients, discovering that 90 were diagnosed with PA, and found a strong correlation in aldosterone measurements between the two tests.
- The ADRR method proved to be accurate, achieving a sensitivity of 91% and specificity of 85%, making it a reliable option for diagnosing PA alongside the established RIA method.