Advances in the Treatment of Congenital Infiltrating Lipomatosis of the Face: The Role of PIK3CA Mutations and Microvascular Reconstruction.

Congenital infiltrating lipomatosis of the face is a rare aggressive-benign disorder characterized by progressive hemifacial overgrowth and complex, often asymmetrical, facial differences. Recently linked with the PIK3CA-Related Overgrowth Spectrum, it arises from mosaic mutations in the PIK3CA gene. Treatment, largely supportive and tailored to individual clinical presentations, requires a multidisciplinary approach.

Management of Intraoperative Contamination of the Custom Total Temporomandibular Joint Prosthesis.

Management of intraoperative contamination of a custom total temporomandibular joint prosthesis has not been reported in the literature. As this complication is rare, it can be unsettling for the surgeon. Improper management may lead to a complicated treatment course and financial consequences.

The Role of Endotracheal Tube in Medication-Related Osteonecrosis of the Jaw - A Case Report.

Rationale: Various traumatic risk factors have been correlated to the development of medication-related osteonecrosis of the jaw (MRONJ), with long-term use of antiresorptive or antiangiogenic medications. No previous cases of MRONJ secondary to endotracheal intubation have been reported in the oral and maxillofacial surgery literature.

Patient Concerns: This case report describes a patient on long-term oral bisphosphonate therapy who presented with a nonhealing ulcer and exposed bony island along her right mandibular torus after undergoing general anaesthesia.

New Developments in Hip Fracture Treatment to Reduce Morbidity and Mortality.

There have been major changes in the treatment of various hip fracture patterns in the proximal femur. The orthopaedic surgeon should be up to date on device management, current guidelines, and techniques in the care of hip fracture patterns.

Langerhans Cell Histiocytosis of the Pediatric Thoracic Spine with Development of Neurological Compromise: A Case Report.

Case: This report describes a 7-year-old girl with Langerhans cell histiocytosis (LCH) of the thoracic spine who developed neurological deterioration during nonsurgical management. She was treated with decompression and instrumented fusion followed by chemotherapy, recovered completely after surgery, and was doing well at 6-year follow-up.

Conclusions: The best treatment of LCH of the spine is not clear, but in the setting of neurologic compromise after failing conservative management, surgical decompression with adjuvant chemotherapy should be considered.