Publications by authors named "J Bures"
Article Synopsis
- Severe alcohol-associated hepatitis (SAH) is a serious condition with high mortality rates, and current treatments like corticosteroids have limited effectiveness, prompting the exploration of new therapies such as fecal microbiota transplantation (FMT).
- This study aimed to investigate the impact of FMT on 30- and 90-day mortality in SAH patients who did not respond to or were ineligible for corticosteroids, as well as to identify outcomes and factors influencing patient survival.
- The research involved a prospective analysis of adult patients receiving FMT, comparing their outcomes with a control group who received standard care, and evaluating various prognostic factors related to SAH outcomes.
Background: Pancreatic ductal adenocarcinoma (PDAC) is associated with a very poor prognosis, with near-identical incidence and mortality. According to the World Health Organization Globocan Database, the estimated number of new cases worldwide will rise by 70% between 2020 and 2040. There are no effective screening methods available so far, even for high-risk individuals.
View Article and Find Full Text PDFBackground: There is no single gold standard for investigation of gastrointestinal motility function. Wireless motility monitoring involves a novel concept which provides a complex information on gastrointestinal function (gastrointestinal transit time, intra-luminal pH, pressure and temperature). Gastrointestinal motility functions of experimental pigs are very similar to those of humans.
View Article and Find Full Text PDFIn this article we report that a cationic version of Akiba's Bi complex catalyzes the reduction of amides to amines using silane as hydride donor. The catalytic system features low catalyst loadings and mild conditions, en route to secondary and tertiary aryl- and alkylamines. The system tolerates functional groups such as alkene, ester, nitrile, furan and thiophene.
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