Publications by authors named "J Bukac"

Background And Aim: Progress in laboratory diagnostics of IgE-mediated allergy is the use of component-resolved diagnosis. Our study analyses the results of specific IgE to 295 allergen reagents (117 allergenic extracts and 178 molecular components) in patients suffering from atopic dermatitis (AD) with the use of ALEX2 Allergy Explorer.

Method: The complete dermatological and allergological examination, including the examination of the sensitization to molecular components with ALEX2 Allergy Explorer testing, was performed.

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Progress in laboratory diagnostics of IgE-mediated allergies is being made through the use of component-resolved diagnosis. The aim of our study is to analyze the sensitization profile to allergen reagents in patients suffering from atopic dermatitis with the use of the ALEX 2-Allergy Explorer and especially to show the sensitization to molecular components of molds and yeast. The complete dermatological and allergological examination including the examination of the sensitization to allergen reagents with Allergy Explorer ALEX 2 testing was performed.

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Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease. The progression from AD to bronchial asthma (AB) and allergic rhinitis (AR) is called atopic march. The aim of this study was to evaluate the difference in the sensitization to molecular components in patients suffering from AD in relation to subgroups of patients with AR and AB.

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Article Synopsis
  • - The study evaluated melanoma trends in East Bohemia from 2002-2017, focusing on types like nodular, superficial, lentigo maligna, and melanoma in situ, involving 2,230 newly diagnosed patients.
  • - It found an increase in cases of lentigo maligna and melanoma in situ, but no rise in nodular or superficial melanomas, nor an overall increase in total melanoma cases.
  • - The research concluded that age differences were not significant among patients with different melanoma types, and no relationship was found between melanoma occurrence and the number of annual sunshine hours.
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Aim: To evaluate the occurrence of melanoma in the period 1996-2017 in East Bohemia region in the Czech Republic.

Method: We studied the incidence of melanoma and the age of diagnosis (adjusted calculation) and the parameters such as histology, body site of lesions, the length of the duration of lesions in 2810 patients.

Results And Conclusion: No change in the occurrence of melanoma and in age of melanoma during this period was found.

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