Associations between bovine IGFBP2 polymorphisms with fertility, milk production, and metabolic status in UK dairy cows.

Insulin-like growth factor binding protein-2 (IGFBP2) is a key regulator of IGF activity that has been associated with insulin resistance and obesity. In cows, IGFBP2 mRNA expression is differentially regulated according to nutritional status in different tissues including the liver, reproductive tract, and mammary gland. This study investigated associations between single nucleotide polymorphisms (SNPs) in bovine IGFBP2 with fertility, milk production, and metabolic traits in Holstein-Friesian dairy cows.

Polymorphisms in the autosomal genes for mitochondrial function TFAM and UCP2 are associated with performance and longevity in dairy cows.

The autosomal genes mitochondrial transcription factor A (TFAM) and uncoupling protein 2 (UCP2) are both involved in moderating mitochondrial energy production. This study investigated single nucleotide polymorphisms (SNPs) in TFAM and UCP2 and their associations with growth, fertility, milk production and survival in UK dairy cows. Holstein-Friesian heifers (n = 509) were recruited at birth and monitored until they either reached the end of their second lactation or were culled.

Considering accreditation in gerontology: the importance of interprofessional collaborative competencies to ensure quality health care for older adults.

The health care needs of older adults can be complex and multifaceted. Safe, effective, equitable, and person-centered service provision relies on skilled interprofessional, team-based practice. Too often, students seeking a career specializing in gerontology are not exposed to such interprofessional, team-based learning and practice during their coursework.

Evidence that leptin genotype is associated with fertility, growth, and milk production in Holstein cows.

This study investigated associations between single nucleotide polymorphisms (SNP) in the leptin, leptin receptor, and neuropeptide Y (NPY) genes with growth, milk production, and fertility traits. Holstein Friesian heifers from 19 UK dairy farms were recruited at birth, providing an initial population of 509. Animals were monitored until they either reached the end of their second lactation or were culled.

A descriptive study of the survival of Holstein-Friesian heifers through to third calving on English dairy farms.

A short herd lifespan severely limits opportunities for on-farm selection of breeding cows in addition to causing financial losses on dairy farms and presenting welfare issues for individual animals. This prospective study monitored survival up to third calving and reasons for culling of a cohort of 468 Holstein-Friesian heifers on 18 dairy farms across southern England. Heifers born during 2003 and 2004 were monitored from 1 mo of age through to third calving.