Publications by authors named "J Breza"

Urinary tract infections are one of the most common types of bacterial infections in childhood. Normally, empiric antibiotic therapy is given based on local antimicrobial susceptibility. We performed a retrospective study to evaluate bacterial resistance and clinical responses to antibiotics in childhood febrile urinary tract infections (fUTIs) in the Bratislava region of Slovakia.

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Background: Men with overactive bladder (OAB) and benign prostatic hyperplasia (BPH), will have deterioration in the quality of life.

Objective: The aim of this study was to evaluate the effect of combining pelvic floor muscle training with the urgency suppression technique (PFMT-st) and silodosin in comparison with silodosin in men with benign prostatic hyperplasia (BPH) and overactive bladder (OAB) after 12 weeks of treatment.

Patients And Methods: A total of 158 patients were randomized into two groups.

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Article Synopsis
  • - The study investigates how nerve connections (innervation) affect prostate cancer, noting that while many experiments show nerves influence cancer growth, there's limited information specifically about human prostate cancer innervation.
  • - Analysis of prostate tissue samples revealed a significant decrease in nerve density in cancerous tissues compared to normal tissues and benign prostatic hyperplasia, with various types of nerves detected (sympathetic, parasympathetic, and sensory).
  • - The research suggests that while the pattern of innervation in prostate cancer is similar to that in healthy tissues, the overall nerve presence is much lower, particularly in higher-grade cancer cases, and does not show increased nerve activity linked to cancer proliferation.
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Extracellular DNA (ecDNA) is a promising candidate marker for the early diagnosis and monitoring of urinary tract infections (UTIs). The aim of our study is to describe the dynamics of ecDNA in the plasma and urine of patients with urosepsis as well as in a mouse model of UTI. Samples of blood and urine were collected from adult patients with UTIs and obstructive uropathy (n = 36) during the first 3 days at the hospital and during a follow-up.

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In behavioral experiments, rats perceive sodium carbonate (Na2CO3) as super salty. In fact, when the dissociated Na+ ions are accounted for, rats perceive Na2CO3 as 5× saltier than equinormal concentrations of NaCl. The chorda tympani nerve (CT) responds to salts through at least two receptor mechanisms and is a model system for understanding how salt taste is transmitted to the brain.

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