Publications by authors named "J Breme J"
Purpose: Cartilage repair necessitates adjunct therapies such as cell-based approaches, which commonly use MSCs and chondrocytes but is limited by the formation of fibro-hyaline cartilage. Articular cartilage-derived chondroprogenitors(CPs) offer promise in overcoming this, as they exhibit higher chondrogenic and lower hypertrophic phenotypes. The study aimed to compare the efficacy of various cell types derived from adult and foetal cartilage suspended in platelet-rich plasma(PRP) in repairing chondral defects in an Ex-vivo Osteochondral Unit(OCU) model.
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- The text discusses the physiological and psychological changes during pregnancy and how regular physical activity can reduce the risk of health issues like gestational diabetes and pre-eclampsia.
- A study was conducted on 380 antenatal mothers in Puducherry to evaluate their knowledge and attitude towards physical activity during pregnancy, using a structured questionnaire.
- Results showed that about 51.3% of mothers had adequate knowledge about physical activity, while 79.7% had a favorable attitude, with significant links to factors like education, employment, and pre-existing health conditions.
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- Oral squamous cell carcinoma (OSCC) poses significant challenges for clinicians and pathologists, as illustrated by a unique case involving the left buccal mucosa that included severe bone exposure and skin perforation.
- The case exhibited alarming symptoms such as ulceration, necrosis, and maggot infestation, with histological analysis revealing poorly differentiated malignant cells that indicated a severe form of the disease.
- The report highlights the critical importance of early diagnosis and treatment to halt disease progression, mitigate immune suppression, and enhance patient quality of life.
BACKGROUND: Wilson disease (WD) is a rare disease characterized by impaired copper metabolism. It is usually diagnosed in children and has several distinct attributes that can make the caregiving experience different. The advanced stage of the illness is quite challenging, and caregiver experiences during this phase of the disease are underexplored.
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- - This paper explores the various applications of additive manufacturing (AM) in biomedical engineering, focusing on its transformative effects in areas like organ transplantation and regenerative medicine through bioprinting technologies.
- - It highlights the customization of implants and prosthetics, showing how these tailored medical devices improve patient comfort and surgical precision while discussing the role of 3D-printed models in enhancing surgical outcomes.
- - The review also covers AM's contributions to drug delivery systems and personalized medical products, addressing issues like regulatory frameworks and biocompatibility, while considering the future impact of AM on global health and sustainability.