Publications by authors named "J Brandolini"
In recent years, the use of smartphones has significantly increased among populations of almost every age. The aim of our work is to analyze the impact of an application (app) that follows up with the progress of a patient who underwent a thoracic surgery procedure in the first 30 days after discharge. We prospectively analyzed all the patients included in the pilot study from March 2023 to September 2023.
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- A large multicenter study across 15 Italian hospitals evaluated the early and long-term outcomes of robot-assisted thoracoscopic thymectomy for thymic epithelial tumors, enrolling 669 patients from 2002 to 2022.
- The study found that most patients (98%) underwent complete thymectomy with a low incidence of open conversion (3.4%) and no perioperative mortality; however, 7.7% experienced postoperative complications.
- Results showed effective oncological outcomes with only 2 patients dying from tumor-related causes during follow-up, and the 5- and 10-year recurrence rates were low at 7.4% and 8.3%, respectively, indicating the procedure's safety and effectiveness.
Thymectomy is the gold standard in the treatment of thymic neoplasm and plays a key role in the therapeutic path of myasthenia gravis. For years, sternotomy has been the traditional approach for removing anterior mediastinal lesions, although the robotic thymectomy is now widely performed. The literature is still lacking in papers comparing the two approaches and evaluating long-term oncological and neurological outcomes.
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- Thymic tumours are currently classified mainly by local invasiveness rather than size, prompting a study on how tumour dimensions affect survival rates in surgical patients.
- A retrospective analysis of 332 patients with thymic epithelial tumours found high five- and ten-year overall survival rates, with additional correlations to factors like male sex and older age influencing tumour size.
- Although tumour dimension alone was not a strong predictor of disease-free or overall survival, multivariate analysis suggested it could improve the TNM staging system for these tumours.
Although the WHO has declared the end of the pandemic emergency, COVID-19 still poses a threat to immunocompromised patients. The COVID-19 pandemic has spread throughout the world over the last two years, causing a significant number of deaths. After three years, SARS-CoV-2 has lost its initial lethality but has shown a significantly worse prognosis for immunocompromised patients, especially those who have undergone lung transplantation, compared with the general population.
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