Objectives: To design a remotely operated robot, "HazBot," for bioevent disaster response; specifically, to improve existing commercial robots' capabilities in handling fixed-facility hazmat incidents via a unique robot controller that allows the human operator to easily manipulate HazBot in disaster situations.
Design: The HazBot's design objectives were for a robot to approach a building, open doors, enter, and navigate the building. The robot's controlling device was designed to provide features not available in current robots: dexterous manipulation and enhanced sensory (touch) feedback via "haptic" technology.
Prelamin A processing is unique amongst mammalian proteins and results in the production of a farnesylated and carboxymethylated peptide. We examined the effect of pathogenic LMNA mutations on prelamin A processing, and of the covalently modified peptide on cardiac and skeletal myoblast differentiation. Here we report a mutation associated with dilated cardiomyopathy prevents prelamin A peptide production.
View Article and Find Full Text PDFIntroduction: Since 2003, Iraq has struggled to build a single national health system administered by the Iraqi Ministry of Health, but politics, lack of leadership, and a cultural bias against treating soldiers in civilian hospitals have hindered access to care for members of Iraq's armed forces who are wounded in combat.
Methods: U.S.