Central pain in the face and head.

All kinds of lesions in the central nervous system can induce central neuropathic pain (e.g., stroke, multiple sclerosis, spinal cord injury, syringobulbia, syringomyelia).

Central pain in multiple sclerosis - sensory abnormalities.

Many patients with multiple sclerosis (MS) develop central neuropathic pain (CP). In the present study somatosensory abnormalities have been analysed in detail in 62 patients with MS and CP (42 women, 20 men; mean age 52 years) and in a control group of 10 women and 6 men (mean age 47 years) with MS and sensory symptoms, but without pain. Assessment included clinical testing and quantitative methods (QST) for the measurement of perception thresholds for touch, vibration, and temperatures.