Dalbavancin as sequential therapy in infective endocarditis: Real-life experience in elder and comorbid patients.

Objectives: This study aimed to evaluate the effectiveness of dalbavancin as sequential therapy in patients with infective endocarditis (IE) due to gram positive bacteria (GPB) in a real-life heterogenous cohort with comorbid patients.

Methods: A single center retrospective cohort study including all patients with definite IE treated with dalbavancin between January 2017 and February 2022 was developed. A 6-month follow-up was performed.

Surgical Treatment of Persistent Pseudomonas aeruginosa Bacteraemia After n-Butyl-2-cyanoacrylate for Gastric Bleeding Varices.

n-Butyl-2-cyanoacrylate (NCBA) is an effective therapeutic option for bleeding gastric varices but can sometimes be associated with adverse effects. Persistent bacteraemia is an unusual complication with a high mortality rate. We report the case of a 34-year-old man with history of cirrhosis due to Wilson's disease and severe portal hypertension who was hospitalized as a result of upper gastrointestinal bleeding secondary to fundic varices that were treated with NCBA.

Effectiveness of ceftazidime-avibactam for the treatment of infections due to Pseudomonas aeruginosa.

Background: Clinical experience with ceftazidime-avibactam (CAZ-AVI) for treatment of infections due to multidrug or extremely resistant (MDR/XDR) Pseudomonas aeruginosa (P. aeruginosa) is limited.

Methods: A retrospective cohort study was conducted on patients with MDR/XDR P.

Baclofen reduces binge eating in a double-blind, placebo-controlled, crossover study.

Baclofen has shown promise in treating substance use disorders and also reduced binge frequency in an open-label trial. This placebo-controlled, double-blind, crossover study further assessed the effects of baclofen on binge eating. Twelve individuals who self-reported binge eating completed the study.

Practices associated with weight loss versus weight-loss maintenance results of a national survey.

Background: Few studies have examined the weight-control practices that promote weight loss and weight-loss maintenance in the same sample.

Purpose: To examine whether the weight control practices associated with weight loss differ from those associated with weight-loss maintenance.

Methods: Cross-sectional survey of a random sample of 1165 U.