The conformation of the nSrc specificity-determining loop in the Src SH3 domain is modulated by a WX conserved sequence motif found in SH3 domains.

Cellular signaling networks are modulated by multiple protein-protein interaction domains that coordinate extracellular inputs and processes to regulate cellular processes. Several of these domains recognize short linear motifs, or SLiMs, which are often highly conserved and are closely regulated. One such domain, the Src homology 3 (SH3) domain, typically recognizes proline-rich SLiMs and is one of the most abundant SLiM-binding domains in the human proteome.

Improvement of serum folate status in the US women of reproductive age with fortified iodised salt with folic acid (FISFA study).

Objective: Mandatory folic acid fortification of enriched grains has reduced neural tube defect prevalence in several countries. We examined salt as an additional vehicle for folic acid fortification. The primary objective was to examine the change in serum folate concentration after 1 month of consumption of fortified iodised salt with folic acid (FISFA) among women of reproductive age.

Variation in Lipid Peroxidation in the Ejaculates of Wild Banded Mongooses (): A Test of the Oxidative Shielding Hypothesis.

Reproductive activity is costly in terms of future reproduction and survival. Oxidative stress has been identified as a likely mechanism underlying this cost of reproduction. However, empirical studies have yielded the paradoxical observation that breeders often sustain lower levels of oxidative damage than non-breeders.