Background: Spinal stabilization in dogs is challenging, and improper implant placement can result in significant morbidity. Objectives were to evaluate reliability of a ball-tipped probe for detection of breached versus non-breached pedicle drill tracts in a canine large breed cadaveric model. CT scans obtained from T6 to sacrum.
View Article and Find Full Text PDFRegeneration of hyaline cartilage in human-sized joints remains a clinical challenge, and it is a critical unmet need that would contribute to longer healthspans. Injectable scaffolds for cartilage repair that integrate both bioactivity and sufficiently robust physical properties to withstand joint stresses offer a promising strategy. We report here on a hybrid biomaterial that combines a bioactive peptide amphiphile supramolecular polymer that specifically binds the chondrogenic cytokine transforming growth factor β-1 (TGFβ-1) and crosslinked hyaluronic acid microgels that drive formation of filament bundles, a hierarchical motif common in natural musculoskeletal tissues.
View Article and Find Full Text PDFBone morphometry varies among dogs of different sizes and breeds. Studying these differences may help understand the predisposition of certain breeds for specific orthopedic pathologies. This study aimed to develop a statistical shape model (SSM) of the femur, patella, and tibia of dogs without any clinical orthopeadic abnormalities to analyze and compare morphological variations based on body weight and breed.
View Article and Find Full Text PDFObjective: To evaluate the feasibility of endoscopic inspection of thoracolumbar and lumbar pedicle tracts in a canine large-breed model and its accuracy for the detection of breached versus nonbreached tracts.
Animals: 2 greyhound cadavers.
Methods: CT scans of 2 greyhound cadavers from the sixth thoracic vertebra to the sacrum were obtained.
Objective: To compare the accuracy of three-dimensional (3D) printed patient-specific guide (PSG) with a freehand (FH) approach for radial osteotomies in ex vivo normal dogs.
Study Design: Experimental study.
Animals: Twenty four ex vivo thoracic limb pairs from normal beagle dogs.