Publications by authors named "J Bellec"

Article Synopsis
  • Some patients with serious heart problems were treated with a special radiation therapy for their heart issues, but we didn't know how many of them would survive for a year after the treatment.
  • After looking at different studies, researchers found that about 32% of these patients died within a year, with most deaths happening in the first three months.
  • The main reason for these deaths was worsening heart failure, but many also died from other health issues, especially in patients over 70 years old.
View Article and Find Full Text PDF

Left ventricular assist device (LVAD) implantation is an established treatment for patients with advanced heart failure refractory to medical therapy. However, the incidence of ventricular arrhythmias (VAs) is high in this population, both in the acute and delayed phases after implantation. About one-third of patients implanted with an LVAD will experience sustained VAs, predisposing these patients to worse outcomes and complicating patient management.

View Article and Find Full Text PDF

Background: Cardiac radioablation (CR) is an innovative treatment to ablate cardiac arrythmia sources by radiation therapy. CR target delineation is a challenging task requiring the exploitation of highly different imaging modalities, including cardiac electro-anatomical mapping (EAM).

Purpose: In this work, a data integration process is proposed to alleviate the tediousness of CR target delineation by generating a fused representation of the heart, including all the information of interest resulting from the analysis and registration of electro-anatomical data, PET scan and planning computed tomography (CT) scan.

View Article and Find Full Text PDF
Article Synopsis
  • Monoclonal antibodies (mAbs) are increasingly important in cancer therapy, and ensuring their quality is crucial for patient safety.
  • The study investigates the use of image capillary isoelectric focusing (icIEF) combined with statistical methods (PCA and PLS-DA) to effectively characterize and identify different mAbs in a clinical setting.
  • Results showed that this method can accurately distinguish various commercial mAbs and predict which one is being analyzed, proving to be a reliable approach for verifying mAbs before administration to patients.
View Article and Find Full Text PDF