Publications by authors named "J Begum-Ali"
Infants at elevated likelihood for or later diagnosed with autism typically have smaller vocabularies than their peers, as shown by the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI). However, the extent to which MSEL and CDI scores align remains unclear, especially across clinical and non-clinical populations. This study examined whether the concurrent validity of the MSEL and CDI differs based on autism likelihood and diagnosis.
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- Children with Neurofibromatosis 1 (NF1) show distinct cognitive, behavioral, and social differences from typically developing peers, with the study focusing on the emergence of these differences in children aged 5 to 36 months.
- The study found that NF1 children significantly lagged in cognitive and behavioral skills compared to typically developing children, particularly evident by 24 months, and exhibited higher traits associated with ADHD and autism, with 14% diagnosed with autism by 36 months.
- Limitations include a small sample size and the use of an online assessment tool for autism symptoms, which may affect the accuracy of the findings, especially since 41% of NF1 children were assessed with this method at
This study examined the recurrence rate of autism in siblings at elevated likelihood (EL) and the predictive validity of the Q-CHAT and ADOS-2 at 14 and 24 months (m) for a clinical best estimate (CBE) autism diagnosis at 3 years. 331 EL-siblings (47.9% girls) from the prospective longitudinal EuroSibs study underwent ADOS-2 assessments and caregivers completed the Q-CHAT at 14 m and 24 m.
View Article and Find Full Text PDFBackground: Data sharing in developmental science is increasingly encouraged, supported by funder and publisher mandates for open data access. Data sharing can accelerate discovery, link researchers with high quality analytic expertise to researchers with large datasets and democratise the research landscape to enable researchers with limited funding to access large sample sizes. However, there are also significant privacy and security concerns, in addition to conceptual and ethical considerations.
View Article and Find Full Text PDFBackground: Existing evidence indicates that atypical sensory reactivity is a core characteristic of autism, and has been linked to both anxiety (and its putative infant precursor of fearfulness) and repetitive behaviours. However, most work has used cross-sectional designs and not considered the differential roles of hyperreactivity and hyporeactivity to sensory inputs, and is thus limited in specificity.
Methods: 161 infants with and without an elevated likelihood of developing autism and attention-deficit hyperactivity disorder (ADHD) were followed from 10 to 36 months of age.