Towards an optimized security approach to IoT devices with confidential healthcare data exchange.

Reliable data exchange and efficient image transfer are currently significant research challenges in health care systems. To incentivize data exchange within the Internet of Things (IoT) framework, we need to ensure data sovereignty by facilitating secure data exchange between trusted parties. The security and reliability of data-sharing infrastructure require a community of trust.

Cell-mediated enzyme prodrug cancer therapies.

Cell-directed gene therapy is a promising new frontier for the field of targeted cancer therapies. Here we discuss the current pre-clinical and clinical use of cell-mediated enzyme prodrug therapy (EPT) directed against solid tumors and avenues for further development. We also discuss some of the challenges encountered upon translating these therapies to clinical trials.

Vaccine Failures in Patients Properly Vaccinated with 13-Valent Pneumococcal Conjugate Vaccine in Catalonia, a Region with Low Vaccination Coverage.

Vaccine failures occurring with 13-valent pneumococcal conjugate vaccine (PCV13) in 3 pediatric hospitals in Barcelona (2012-2013) are described. PCV13 vaccine failure was defined as the occurrence of an invasive pneumococcal infection in children properly vaccinated by PCV13. Among 84 patients with invasive pneumococcal infection, 32 had received at least one dose of PCV13.

Encapsulation efficiency of CdSe/ZnS quantum dots by liposomes determined by thermal lens microscopy.

In this study the encapsulation of core shell carboxyl CdSe/ZnS quantum dots (QDs) by phospholipids liposome complexes is presented. It makes the quantum dots water soluble and photo-stable. Fluorescence self-quenching of the QDs inside the liposomes was observed.

[Prevention of serogroup B meningococcal disease using a four-component vaccine].

Introduction: Meningococcal disease is an infection caused by Neisseria meningitidis, and those of serogroup B are currently the most predominant. It has been difficult to create effective vaccines for this serogroup in order to modify or reduce its morbidity. The aim of this study was to review existing data on the new vaccine 4CMenB and its potential contribution to the prevention of this infection.