Liquid crystal elastomers (LCEs) exhibit reversible shape morphing behavior when cycled above their nematic-to-isotropic transition temperature. During extrusion-based 3D printing, LCE inks are subjected to coupled shear and extensional flows that can be harnessed to spatially control the alignment of their nematic director along prescribed print paths. Here, we combine experiment and modeling to elucidate the effects of ink composition, nozzle geometry, and printing parameters on director alignment.
View Article and Find Full Text PDFInsights into the identification, prevention, and treatment of neurovascular compromise in upper extremity surgery are provided in this chapter, focusing on commonly encountered injuries susceptible to intraoperative or postoperative issues. The authors highlight the importance of knowledge of anatomy, meticulous dissection, and preparation to navigate complex surgical scenarios effectively. Furthermore, proactive approaches to managing difficult situations encountered during surgery are outlined, emphasizing timely recognition and decisive action.
View Article and Find Full Text PDFBackground: The difficult airway is frequently encountered across many scenarios. The extreme form is a "cannot intubate and cannot oxygenate" scenario, which lacks a reliable rescue technique. Previous case reports or studies with small sample sizes indicate the feasibility and efficiency of an endotracheal tube in the pharynx (TTIP) to ventilate patients.
View Article and Find Full Text PDFC-X-C motif chemokine ligand 12 (CXCL12; Stromal Cell-Derived Factor 1 [SDF-1]), most notably known for its role in embryogenesis and hematopoiesis, has been implicated in tumor pathophysiology and neovascularization. However, its cell-specific role and mechanism of action have not been well characterized. Previous work by our group has demonstrated that hypoxia-inducible factor (HIF)-1 modulates downstream CXCL12 expression following ischemic tissue injury.
View Article and Find Full Text PDFBackground: Homework is implemented with variable effectiveness in real-world therapy settings, indicating a need for innovative solutions to homework challenges. We developed Adhere.ly, a user-friendly, Health Insurance Portability and Accountability Act-compliant web-based platform to help therapists implement homework with youth clients and their caregivers.
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