Publications by authors named "J Banton"

Article Synopsis
  • The study reviews the use of hyaluronic acid as a nonsurgical treatment in urology, highlighting its potential and the current state of research.
  • A comprehensive analysis was conducted on 33 studies, focusing on metrics such as penile girth and ejaculatory latency, with most studies showing positive outcomes and rare complications.
  • Despite encouraging results, variability in study quality is noted, emphasizing the need for standardized approaches in future randomized controlled trials.
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Introduction: Multiple sclerosis (MS) is a chronic autoimmune disease that affects the central nervous system and is widely recognized as a disease primarily affecting women. The relationship between MS and hypogonadism is complex and not fully understood, with recent evidence showing that hypogonadism may have a significant impact on the quality of life and disease progression of patients with MS.

Objectives: This review aims to provide an overview of the current knowledge regarding the relationship between MS and hypogonadism, including the mechanisms underlying this relationship; the effects of hypogonadism on patients with MS; and the potential benefits and drawbacks of testosterone replacement therapy for patients with MS and hypogonadism.

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Article Synopsis
  • Acute decompensated aortic stenosis (ADAS) leads to higher mortality and longer hospital stays compared to stable aortic stenosis (AS), and this study aimed to reduce hospital length of stay (LoS) with a new treatment pathway.
  • The ASTRID-AS pathway expedited the treatment process for ADAS patients, significantly cutting down the time to transcatheter aortic valve implantation (TAVI) and decreasing hospital LoS compared to a conventional approach.
  • While the dedicated pathway saved an average of 13.4 bed days per patient and did not compromise safety, there was a slight increase in acute kidney injury or death within 30 days post-TAVI for the ASTRID-AS cohort.
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Ubiquitin C-terminal hydrolase L1 (UCHL1) is a unique brain-specific deubiquitinating enzyme. Mutations in and aberrant function of UCHL1 have been linked to many neurological disorders. UCHL1 activity protects neurons from hypoxic injury, and binding of stroke-induced reactive lipid species to the cysteine 152 (C152) of UCHL1 unfolds the protein and disrupts its function.

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Central venous catheters (CVCs) are commonly used to deliver a variety of therapies such as chemotherapy and parenteral nutrition. It is well known that there are complications associated with CVCs; a major complication is catheter-related bloodstream infection (CRBSI). Many strategies exist to prevent CVC complications and CRBSI.

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