Publications by authors named "J Bailey-Serres"
Article Synopsis
- - Multicellular organisms, like plants, use specialized barriers in their cells to interact with the environment, with the endodermal Casparian strip (CS) being a key feature in plant roots.
- - In tomato plants, researchers found that instead of forming a CS, the exodermis creates a polar lignin cap (PLC) that has a similar protective function but is regulated differently at the genetic level.
- - While both the exodermis and endodermis create barriers that limit mineral ion uptake, the exodermal PLC can't fully replace the endodermal CS, suggesting that these unique lignin structures play important roles in how roots respond to environmental challenges.
Plant cells regularly encounter hypoxia (low-oxygen conditions) as part of normal growth and development, or in response to environmental stresses such as flooding. In recent years, our understanding of the multi-layered control of hypoxia-responsive gene expression has greatly increased. In this Update, we take a broad look at the epigenetic, transcriptional, translational, and post-translational mechanisms that regulate responses to low-oxygen levels.
View Article and Find Full Text PDFAspirations for high crop growth and yield, nutritional quality and bioproduction of materials are challenged by climate change and limited adoption of new technologies. Here, we review recent advances in approaches to profile and model gene regulatory activity over developmental and response time in specific cells, which have revealed the basis of variation in plant phenotypes: both redeployment of key regulators to new contexts and their repurposing to control different slates of genes. New synthetic biology tools allow tunable, spatiotemporal regulation of transgenes, while recent gene-editing technologies enable manipulation of the regulation of native genes.
View Article and Find Full Text PDFArticle Synopsis
- Visualizing spatial assay data in anatomical images enhances the understanding of biological processes in cell and tissue organization, essential for various experimental technologies like RNA-seq and proteomics.
- The software offers methods to color spatial features in images according to biomolecule abundance, using a spatial heatmap plot and allows for co-visualization of single-cell data and high-dimensional embedding plots.
- It features an automated identification system for biomolecules with selective abundance patterns and is accessible through both a graphical interface for non-experts and a command-line interface for advanced users, distributed as a free, open-source Bioconductor package.