Publications by authors named "J Backmann"

Research suggests that teams can greatly enhance their performance through boundary management, which comprises activities that establish, maintain, and regulate linkages with the surrounding environment. However, such performance gains do not materialize equally in all instances, and some teams struggle to benefit from boundary management. Integrating insights from social network and team-level resource allocation theories, we develop a contingency framework that considers the internal organization of a team's boundary management (i.

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  • Tic disorders (TD) can significantly affect individuals and society, and understanding their genetic causes could lead to better treatments, as family history is a key risk factor.
  • A large-scale GWAS meta-analysis was conducted with nearly 10,000 TD cases and over 981,000 controls, revealing a significant genetic association, though it couldn't be replicated in another study.
  • The findings suggest a complex genetic landscape for TD, highlighting certain genes and brain regions involved, but additional research is needed to firmly establish reliable genetic links.
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  • * A genome-wide association meta-analysis of nearly 122,000 ANX cases revealed 58 significant genetic variants and 66 related genes, with many of these findings replicated in a larger independent sample.
  • * The findings indicate a substantial genetic overlap between ANX and other conditions like depression, emphasizing GABAergic signaling as a key mechanism, thereby enhancing our understanding of the genetic basis of ANX for future research.
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In-vitro diagnostic assays involve various substances that may be released into the environment via a sewage treatment plant if the effluent from diagnostic instruments is discharged into the drains. Because the release of liquid waste into the public sewer system is regulated at national and/or local levels, a risk assessment per site should be performed to determine whether the release of the effluent from in-vitro diagnostic equipment is compliant with applicable regulations. To facilitate the assessment, we developed a screening tool to generate exposure scenarios for chemical substances used in in-vitro diagnostic assays.

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