Publications by authors named "J BROCHIER"
Article Synopsis
- The text discusses limited findings on how Stone Age communities viewed domestic and functional structures, with a focus on new discoveries in Jordan and Saudi Arabia.* -
- Researchers found the oldest known realistic engravings depicting 'desert kites', which are large, humanmade traps dated to at least 9,000 years ago.* -
- These engravings showcase advanced spatial awareness and architectural skills in early humans, offering insights into their understanding of space and community activities.*
Soot marks, witnesses of past human activities, can sometimes be noticed in concretions (speleothem, travertine, carbonated crust, etc.) formed in cavities. We demonstrate here that these deposits, generally ignored in archaeological studies, turned out to be a perfectly suitable material for micro-chronological study of hominin activities in a site.
View Article and Find Full Text PDFThe high selenium content of the Brazil nut, Bertholletia excelsa, makes this seed a healthy food qualified as an antiradical protector. The studied nut contained 126 ppm of selenium. Selenium was found to be distributed in the nut protein fractions.
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- Type 1 (T1) cytokine responses are essential for clearing hepatitis C virus but can also lead to liver damage, making the balance between T1 and T2 responses important for treatment outcomes.
- A pilot study was conducted on treatment-naïve hepatitis C patients receiving IFN alpha 2b and ribavirin to identify immunological markers that could predict therapy success.
- Key findings showed that high baseline levels of sCD30 were associated with better virological responses to treatment, indicating that a T2 cytokine profile may enhance the effectiveness of therapy.
This study compared plasma bioavailable interleukin (IL)-6 levels in 3 groups: human immunodeficiency virus (HIV)-infected patients who had a human herpesvirus (HHV)-associated immune restoration disease (IRD) during highly active antiretroviral therapy (HAART); patients who experienced an IRD initiated by Mycobacterium avium complex, hepatitis C virus, or human papillomavirus; and control patients who had uneventful immune reconstitution. Total IL-6, soluble IL-6 receptor (sIL-6R), and soluble gp130 were measured by ELISA, and levels of free IL-6 and sIL-6/IL-6R complex were modeled mathematically. Persons who had an HHV-associated IRD had increased plasma bioavailable IL-6 before HAART, compared with patients who experienced a non-HHV-associated IRD and with control patients, and their plasma bioavailable IL-6 increased progressively over 3-4 years of treatment.
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